PROJECT 1

$492,623P50FY2013GMNIH

University Of California Berkeley, Berkeley CA

Investigators

Linked publications, trials & patents

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Abstract

Summary Our overall project goal is to systematically link c/s-regulatory elements iri pre-mRNAs to RNA structural features that control alternative pre-mRNA splicing in human cells. While the role of pre-mRNA structure in control of splicing events has been studied for individual genes, a comprehensive understanding of the interplay of RNA structure with splicing control¿and its relation to genetic variation¿is not known for the human transcriptome.

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