Biomedical Informatics

$122,775P50FY2013CANIH

Ohio State University, Columbus OH

Investigators

Linked publications, trials & patents

Paper 39367245 Paper 39283025 Paper 38649282 Paper 38388168 Paper 38205007 Paper 38017103 Paper 37196637 Paper 36823396 Paper 35792553 Paper 35788257 Paper 35718419 Paper 35524992 Paper 34374082 Paper 34261293 Paper 34229733 Paper 34162404 Paper 33683341 Paper 33277314 Paper 33020282 Paper 32759975 Paper 32414849 Paper 31462731 Paper 31413100 Paper 31164409 Paper 30882246 Paper 30821551 Paper 30737482 Paper 30291333 Paper 30139811 Paper 29872168 Paper 29567781 Paper 29563537 Paper 29296862 Paper 29296820 Paper 29296799 Paper 28533390 Paper 28522575 Paper 28486043 Paper 28473620 Paper 28336936 Paper 28321123 Paper 27917390 Paper 27843138 Paper 27784745 Paper 27773928 Paper 27624549 Paper 27517749 Paper 27470602 Paper 27435003 Paper 27358488 Paper 27354268 Paper 27136276 Paper 26840503 Paper 26784138 Paper 26782640 Paper 26669971 Paper 26583570 Paper 26536822 Paper 26449661 Paper 26442611 Paper 26350141 Paper 26202978 Paper 26182309 Paper 26172401 Paper 26158860 Paper 26139325 Paper 26116658 Paper 26065659 Paper 26055302 Paper 25972157 Paper 25971362 Paper 25891862 Paper 25833959 Paper 25788829 Paper 25787252 Paper 25721902 Paper 25716206 Paper 25708835 Paper 25700432 Paper 25669927 Paper 25660723 Paper 25596730 Paper 25595892 Paper 25513467 Paper 25512507 Paper 25486872 Paper 25393910 Paper 25368506 Paper 25301708 Paper 25294898 Paper 25293770 Paper 25271622 Paper 25263557 Paper 25258342 Paper 25204569 Paper 25178460 Paper 25146490 Trial NCT01886859 Trial NCT01515176 Trial NCT01351896

Abstract

The primary objective of the Biomedical Informatics Core (BMIC) is to facilitate the collection, management, integration, and analysis of a complete spectrum of information types required for the efficient operation of the SPORE'S projects, pilots, and other cores. Examples of these information types include structured and semi-structured data sets resulting from: 1) experimental studies; 2) biostatistical analyses; 3) tissue core and administrative operations; 4) shared resource services; and 5) the asynchronous collaboration of SPORE participants. We will achieve this objective using a combination biomedical informatics best practices and advanced technologies already in use or under development within The Ohio State University (OSU) Department of Biomedical Informatics (OSU-BMI) and The Ohio State University Comprehensive Cancer Center (OSU-CCC). Such technologies include: 1) the service-oriented caGrid middleware for electronic data interchange between heterogeneous biomedical data sources and analytical services; 2) advanced database management systems optimized for the storage and query of rapidly evolving biomedical data sets; 3) centralized ontology services and ontology-anchored knowledge discovery/management tools; 4) multiple task-specific web-portal applications that support the discovery, integration, and analysis of large scale, multi-dimensional data sets; and 5) web-based collaborative team-science tools. We envision the BMIC as being the central information coordination hub of the SPORE. In order to achieve these objectives, the specific aims of the biomedical informatics core are to: 1) develop and support extensible database management systems for use by SPORE participants; 2) enable electronic data interchange between SPORE-related data sources; 3) support task-specific web portal applications that allow end users to discover, integrate, and analyze SPORE-related data sources; 4) support the execution of SPORE-related clinical trials through the facilitation of access to the OSU-CCC's enterprise-grade clinical trials management system; and 5) implement and support a collaborative web portal intended to serve as a medium for both team-science and public dissemination activities.

View original record on NIH RePORTER →