RENAL PROTECTIVE EFFECTS OF LOSARTAN IN PATIENTS WITH NIDDM AND NEPHROPATHY

$0M01FY2001RRNIH

Washington University, Saint Louis MO

Investigators

Linked publications & trials

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Abstract

This study is designed to demonstrate that losartan compared to placebo will reduce the number of NIDDM patients with nephropathy who experience doubling of serum creatinine, ESRD (dialysis, transplantation) or death. This study will also investigate the effect of losartan compared to placebo or cardiovascular morbidity and mortality, proteinuria and safety and tolerability. Tertiary parameters include quality of life and healthcare resource utilization.

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