Infections, immunity, and inflammation in cancer

$1,348,235ZIAFY2012CANIH

Division Of Cancer Epidemiology And Genetics

Investigators

Linked publications & trials

Paper 38847607 Paper 38372706 Paper 38070489 Paper 37944040 Paper 37701981 Paper 37615573 Paper 37492080 Paper 37291711 Paper 37074947 Paper 37067240 Paper 36961501 Paper 36929885 Paper 36804133 Paper 36746336 Paper 35932302 Paper 35788262 Paper 35633044 Paper 35587341 Paper 35071980 Paper 35029169 Paper 34838756 Paper 34430511 Paper 34286851 Paper 33852009 Paper 33549870 Paper 33431958 Paper 33316174 Paper 33084186 Paper 33010161 Paper 32833021 Paper 32710777 Paper 32621759 Paper 32466721 Paper 32401271 Paper 31962125 Paper 31742639 Paper 31709523 Paper 31684770 Paper 31625136 Paper 31054214 Paper 31044245 Paper 31012956 Paper 30826282 Paper 30820931 Paper 30700443 Paper 30655229 Paper 30624768 Paper 30613965 Paper 30345506 Paper 30285034 Paper 30123826 Paper 29982318 Paper 29801099 Paper 29771785 Paper 29325033 Paper 29272472 Paper 29243850 Paper 29239891 Paper 29204603 Paper 29140774 Paper 29017269 Paper 28994104 Paper 28980390 Paper 28952162 Paper 28805292 Paper 28803888 Paper 28753646 Paper 28634198 Paper 28535293 Paper 28464214 Paper 28423403 Paper 28397388 Paper 28394855 Paper 28394489 Paper 28377416 Paper 28334399 Paper 28314823 Paper 28272137 Paper 28131493 Paper 28117886 Paper 28087608 Paper 28060014 Paper 27997697 Paper 27940936 Paper 27891533 Paper 27750296 Paper 27749369 Paper 27606895 Paper 27539828 Paper 27507879 Paper 27418269 Paper 27197296 Paper 27187086 Paper 27160653 Paper 27062091 Paper 27018254 Paper 26950314 Paper 26818209 Paper 26784951 Paper 26711330

Abstract

Infection, immune disturbances, and inflammation overlap in the ways that they damage tissues and promote development of cancer. Major studies under this project include the HIV/AIDS Cancer Match Study and Transplant Cancer Match Study, which link population-based registries of HIV infected people and transplant recipients to cancer registries in the U.S. Additional studies characterize risk factors for specific cancers in these immunosuppressed populations. Risk of non-Hodgkin lymphoma and lung cancer is elevated in immunosuppressed populations. Other cancers of interest, because they are associated with HIV or organ transplant, include Kaposi sarcoma, liver cancer, cancers related to human papillomavirus (such as cervical cancer and anal cancer), Hodgkin lymphoma, melanoma, non-melanoma skin cancers, kidney cancer, and multiple myeloma. Some studies under this project address the role of chronic infections, immune disturbance, and inflammation in these and other cancers. One study under this project is a case-control study of GB virus C and non-Hodgkin lymphoma. Other studies, which focus on cancer risk in the elderly, involve analyses of linked SEER Medicare registry data.

View original record on NIH RePORTER →