Imaging T Cell Targeting and Function in Human Cancer

$216,969P50FY2012CANIH

Sloan-Kettering Inst Can Research, New York NY

Investigators

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Abstract

Research Project 1 (RP1) builds on the progress and success of Projects 1 and 2 in ICMIC-2. Our hypothesis is that both constitutive and PSMA-activated reporter gene imaging of PSMA directed T cell targeting, distribution and persistence can be performed concurrently in patients with castrate resistant prostate cancer. The central theme of this proposal is consistent with our ICMIC:

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