Biomarkers for Alcohol and Alcoholic Liver Disease

Echelon Biosciences, Inc., Salt Lake City UT

Investigators

Abstract

There needs to better biomarkers of alcohol consumption and alcohol induced organ damage. PEth is a nonoxidative, long-lasting metabolite of ethanol consumption and alcohol related organ damage. PEth may also play a role in cell and organ damage. In this contract antibodies are made to PEth for ELISA research. A cell-based clinical assay for rapid quantification of PEth from blood samples will be generated. This ethanol biomarker assay should then be validated to identify heavy to moderate drinkers.