Biosample

$97,542P30FY2012CANIH

Fox Chase Cancer Center, Philadelphia PA

Investigators

Linked publications, trials & patents

Paper 39604567 Paper 39602533 Paper 39554190 Paper 39546469 Paper 39521739 Paper 39514554 Paper 39371220 Paper 39345610 Paper 39343653 Paper 39223207 Paper 39207123 Paper 39189642 Paper 39148468 Paper 39137728 Paper 39072643 Paper 39060143 Paper 39013784 Paper 39003201 Paper 38982062 Paper 38976159 Paper 38963567 Paper 38914477 Paper 38871720 Paper 38865671 Paper 38853421 Paper 38835516 Paper 38815457 Paper 38811332 Paper 38798370 Paper 38766032 Paper 38747616 Paper 38678525 Paper 38659828 Paper 38639476 Paper 38638131 Paper 38600381 Paper 38586274 Paper 38586042 Paper 38559274 Paper 38547779 Paper 38539515 Paper 38464238 Paper 38452871 Paper 38432028 Paper 38421650 Paper 38377387 Trial NCT04290585 Trial NCT03177057 Trial NCT02594826 Trial NCT02132884 Trial NCT02132858 Trial NCT02132845 Trial NCT02110953 Trial NCT02092714 Trial NCT02050009 Trial NCT01982591 Trial NCT01962948 Trial NCT01934179 Trial NCT01840150 Trial NCT01462630 Trial NCT01316757 Trial NCT01212822 Trial NCT00750009 Trial NCT00509626 Trial NCT00458588 Trial NCT00436397 Trial NCT00433524 Trial NCT00084591 Trial NCT00084539 Trial NCT00084526 Trial NCT00084513 Trial NCT00066677 Trial NCT00062322 Trial NCT00062309 Trial NCT00043108 Trial NCT00039520 Trial NCT00039507 Trial NCT00022308 Trial NCT00021398 Trial NCT00021372 Trial NCT00021346 Trial NCT00021333 Trial NCT00021320 Trial NCT00005037 Trial NCT00003264 Trial NCT00003263 Trial NCT00003109 Patent 9533040 Patent 9182383 Patent 9101603 Patent 8980258 Patent 8685658 Patent 8609437 Patent 8580263 Patent 8329873 Patent 7332585 Patent 7332580 Patent 7129057 Patent 6946275 Patent 6617427

Abstract

Fox Chase Cancer Center (FCCC) established biospecimen banking activities in 1987 to coordinate the ethical collection, storage, annotation, and distribution of tissue and peripheral blood samples to support translational research. This centralized, Center-wide activity is under the supervision of Boyd (Leader, Women's Cancer (WC) Program) within the Department of Pathology, and is overseen by an interprogrammatic Facility Advisory Committee (FAC). The Biosample Repository Facility (BRF) is a College of American Pathologists (CAP)-accrediled and CLIA-certified Facility that has two major functions: 1) identify participants, obtain informed consent, collect tissue, blood, and/or urine samples from selected populations, and obtain information on personal and family histories of cancer, clinical intervention, and lifestyle factors for use in research; and 2) process and store human biospecimens obtained through investigator-initiated studies. Working in collaboration with pathologists, medical oncologists, surgeons and other hospital personnel, specially trained BRF staff obtain subject informed consent, collect samples, and assemble comprehensive clinical, pathological, and personal/demographic information about each donor and the corresponding samples. As part of this banking process, the BRF staff provides: 1) outstanding diagnostic pathology support; 2) a comprehensive informed consent process for the appropriate use of tissue, blood, and other biospecimens for research; 3) a specialized biospecimen bank devoted to the collection and distribution of specimens to support research; and 4) extensive supporting data from the clinical record and self-reported health history of each participant. All specimens are linked to comprehensive clinical databases supported by the Population Studies Facility (PSF). The BRF currently houses over 11,000 fresh-frozen tissue samples, over 29,000 blood samples, and has access to >100,000 surgical pathology cases. The BRF has served 26 FCCC investigators (24 peer-reviewed, funded in CY 2009) across all five CCSG Programs. Ninety-six percent (96%) of the BRF's CY, 2009 use is by peer-reviewed, funded investigators. (See usage table Section V).

View original record on NIH RePORTER →