Patient Oriented Research in Kidney Disease

$113,767K24FY2012DKNIH

University Of California, San Francisco, San Francisco CA

Investigators

Linked publications & trials

Paper 37768189 Paper 37429030 Paper 37357351 Paper 37230949 Paper 37178093 Paper 36100915 Paper 35817274 Paper 35296554 Paper 34897925 Paper 34676697 Paper 34117078 Paper 33044519 Paper 32800842 Paper 32778062 Paper 32707221 Paper 32228497 Paper 32130245 Paper 32082553 Paper 31732235 Paper 31621048 Paper 30993232 Paper 29890946 Paper 29784617 Paper 29699885 Paper 29615268 Paper 29352593 Paper 29217305 Paper 28795146 Paper 28674037 Paper 28473636 Paper 28371433 Paper 28336719 Paper 28254771 Paper 28182808 Paper 28007193 Paper 27927600 Paper 27872156 Paper 27717485 Paper 27516235 Paper 27489301 Paper 27479614 Paper 27475659 Paper 27340288 Paper 27073197 Paper 26933189 Paper 26830447 Paper 26683890 Paper 26651991 Paper 26604213 Paper 26558369 Paper 26538631 Paper 26494562 Paper 26307607 Paper 26134154 Paper 26054540 Paper 25589150 Paper 25577135 Paper 25493952 Paper 25332181 Paper 25287404 Paper 24709949 Paper 24342932 Paper 24305166 Paper 24200462 Paper 24041612 Paper 23929923 Paper 23883656 Paper 23714195 Paper 23571811 Paper 23531625 Paper 23411431 Paper 23392070 Paper 23344473 Paper 23275377 Paper 23222124 Paper 23108000 Paper 23065498 Paper 22935481 Paper 22684427 Paper 22580783 Paper 22572568 Paper 22499588 Paper 22332158 Paper 22286715 Paper 21958887 Paper 21917174 Paper 21911761 Paper 21906363 Paper 21784836 Paper 21784832 Paper 21725923 Paper 21529727 Paper 21455065

Abstract

DESCRIPTION (provided by applicant): Chi-yuan Hsu, MD, MSc is applying for a Mid-career Investigator Award in Patient Oriented Research (K24) in order to augment his original research and mentorship efforts. The new research to be supported by this grant leverages Dr. Hsu's ongoing funded projects and represents thematic expansions of his prior work. It is also designed to provide training opportunities for mentees. The underlying theme is to advance understanding of the significance and nature of acute deteriorations in kidney function on several fronts. The specific aims are: Aim 1: To determine the population incidence of acute renal failure (ARF)/acute kidney injury (AKI) overall and in clinically important subgroups and to determine potential driving forces behind this. Aim 2: To determine the importance of abrupt loss of renal function as a pathway leading directly from chronic kidney disease (CKD) to end-stage renal disease (ESRD). Aim 3: To determine the extent to which acute kidney function deterioration in the setting of acute heart failure is associated with elevated levels of markers of renal tubular injury. Dr. Hsu has a strong prior track record of mentorship and works within the rich, supportive and collegial institutional environment at UCSF. Funding from this K24 award will permit Dr. Hsu to spend less time on administrative and clinical responsibilities and more time on research and mentoring.

View original record on NIH RePORTER →