Evaluating Safety of Emerging Orthopaedic Technologies

$101,296P60FY2012ARNIH

Dartmouth College, Hanover NH

Investigators

Linked publications, trials & patents

Paper 32949237 Paper 32769595 Paper 31889578 Paper 31500911 Paper 31098595 Paper 30910627 Paper 30824217 Paper 30280136 Paper 30232537 Paper 30100133 Paper 29877995 Paper 29788284 Paper 29652786 Paper 29572037 Paper 29246848 Paper 28991874 Paper 28885288 Paper 28847740 Paper 28801877 Paper 28781014 Paper 28477069 Paper 28399551 Paper 28350635 Paper 28340130 Paper 28336148 Paper 28244911 Paper 28146015 Paper 27831992 Paper 27817993 Paper 27612607 Paper 27584678 Paper 27557452 Paper 27548843 Paper 27370543 Paper 27345747 Paper 27342707 Paper 27018900 Paper 27018897 Paper 26911297 Paper 26729775 Paper 26727925 Paper 26679877 Paper 26656062 Paper 26641853 Paper 26548963 Paper 26547763 Paper 26483260 Paper 26290082 Paper 26173812 Paper 26083472 Paper 25948698 Paper 25822137 Paper 25803767 Paper 25729901 Paper 25692369 Paper 25668333 Paper 25653317 Paper 25639530 Paper 25575086 Paper 25573760 Paper 25569525 Paper 25569524 Paper 25528263 Paper 25523380 Paper 25495552 Paper 25447956 Paper 25349053 Paper 25334052 Paper 25299258 Paper 25271601 Paper 25185600 Paper 25119955 Paper 25080282 Paper 25057116 Paper 25008217 Paper 24978923 Paper 24854312 Paper 24828942 Paper 24809808 Paper 24584921 Paper 24525995 Paper 24373681 Paper 24257678 Paper 24219186 Paper 24210578 Paper 24153171 Paper 23900116 Paper 23846502 Paper 23818190 Paper 23609204 Paper 23578594 Paper 23548543 Paper 23548542 Paper 23542404 Paper 23542402 Paper 23429684 Paper 23379630

Abstract

PROJECT SUMMARY (See instructions): This developmental project seeks to facilitate early detection of serious complications associated with new orthopedic devices. Innovative aspects of the project include validation of administratively-derived safety measures, use of FDA-approval data as a benchmark for monitoring safety, and use of readily-available population-based databases to evaluate the safety of emerging surgical devices. The project implements statistical modeling techniques that leverage medical claims data to continually assess the risks of new devices as additional data is accured on repeat surgery, infection, other complications, and death. We will demonstrate the approach by examining the experience with bone morphogenetic protein, a biological agent used as an adjuncent to spinal fusion surgery

View original record on NIH RePORTER →