LAC REPRESSOR AND MUTANTS IN COMPLEX WITH OPERATOR DNA

$10,975P41FY2011RRNIH

Cornell University, Ithaca NY

Investigators

Linked publications & trials

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Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We aim to solve the structure of the Lac repressor and DNA binding domain mutants in complex with the symmetric operator and symmetric operator variants for use in theoretical studies of protein-DNA interactions.

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