CDB-4776/H2-GAMENDAZOLE 28-DAY DEFINITIVE TOXICOLOGY IN NON RODENT

Sri International, Menlo Park CA

Investigators

Abstract

Biological Testing Facility is designed to permit rapid evaluation of new compositions of matter, drug formulations, delivery systems, and devices for anti-fertility and endocrine activity. NICHD has supported investigators who are aggressively researching different compounds that can disrupt sperm function between geneis and motility, so that safe, effective and inexpensive contraceptives can be offered to men. These include anit-fertility tests in male and female animals, bioassays, mechanism of action studies, radio-immunoassays of steroid and protein hormones, radio-receptor assays, pharmacokinetic studies and drug safety evaluations.