CC: Biostatistics Core

$85,685P50FY2011CANIH

University Of Tx Md Anderson Can Ctr, Houston TX

Investigators

Linked publications & trials

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Abstract

The Biostatistics Core will support the Projects of this SPORE so that research studies are efficiently designed, conducted, monitored and analyzed. Activities will include formalization of hypotheses to be tested to ensure that valid conclusions can be drawn, design of clinical trials and laboratory studies, assessment of measurement protocols for assay development, and data analysis. The Biostatistics Core will provide input into the statistical aspects of the Projects, including experimental design and development and validation of novel measurements, and it will provide innovative and modern statistical analysis of the data. The objective of the Core is to provide statistical support as required by the Projects and Cores to achieve their specific aims. The statistical components of all clinical and laboratory protocols will include determination of the type of design to be used, calculation of number of experimental units (animals or patients) needed, assessment of the types of data to be collected for each study, specification of design parameters such as sample size, type I and type II error rates of tests of hypotheses, and provision for interim analyses when appropriate.

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